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chenodeoxycholic acid-d4 (d4-cdca)  (Cayman Chemical)


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    Structured Review

    Cayman Chemical chenodeoxycholic acid-d4 (d4-cdca)
    Chenodeoxycholic Acid D4 (D4 Cdca), supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/chenodeoxycholic+acid-d4+(d4-cdca)/taurocholic+acid+d4/pm40288662-42-76-89
    Average 90 stars, based on 1 article reviews
    chenodeoxycholic acid-d4 (d4-cdca) - by Bioz Stars, 2026-10
    90/100 stars

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    other:

    Article Title: Effects of pectin methyl-esterification on intestinal microbiota and its immunomodulatory properties in naive mice.
    Article Snippet: 50 μL of the resulting filtrate were taken in a vial with insert, diluted in 200 μL of ultrapure water:acetonitrile:2-propanol (10,6:5, v/ v/v) with 0,625 mg/L of deuterated standards Glycocholic Acid-d4 (GCA-d4), Deoxycholic Acid-d4 (DCA-d4), Chenodeoxycholic Acid-d4 (CDCA-d4), Cholic Acid-d4 (CA-d4), and Ursodeoxycholic Acid-d4 (UDCA-d4) (Cayman Chemical, Ann Abor, Michigan, United States) and centrifuged as previously described.

    Article Title: Effect of Standardized Grape Powder Consumption on the Gut Microbiome of Healthy Subjects: A Pilot Study
    Article Snippet: Cholic acid (CA), chenodeoxycholic acid (CDCA), deoxycholic acid (DCA), lithocholic acid (LCA), ursodeoxycholic acid (UDCA), hyodeoxycholic acid (HDCA), taurocholic acid (TCA), taurochenodeoxycholic acid (TCDCA), taurodeoxycholic acid (TDCA), taurolithocholic acid (TLCA), glycocholic acid (GCA), glycochenodeoxycholic acid (GCDCA), glycodeoxycholic acid (GDCA), taurolithocholic acid (TLCA), glycodeoxycholic acid-d4 (GDCA-D4) and chenodeoxycholic acid-d4 (CDCA-D4) were purchased from Cayman Chemical (MI, USA).

    Article Title: Gly-β-MCA is a potent anti-cholestasis agent against “human-like” hydrophobic bile acid-induced biliary injury in mice
    Article Snippet: Chenodeoxycholic acid-d4 MaxSpec® standard (CDCA-d4, No. 31366), taurochenodeoxycholic acid-d4 MaxSpec® standard, (T-CDCA-d4, No. 31362), ursodeoxycholic acid-d4 MaxSpec® standard (UDCA-d4, No. 31368) and tauroursodeoxycholic acid-d4 MaxSpec® standard (T-UDCA-d4, No. 31564), and lithocholic acid-d4 MaxSpec® standard (LCA-d4, No. 31354) were purchased from Caymen Chemical Company.

    Article Title: Isomers-oriented separation of forty-five plasma bile acids with liquid chromatography-tandem mass spectrometry.
    Article Snippet: Some bile acids (BAs) were considered as biomarkers or have therapeutical effect on metabolic diseases.. However, due to the existence of isomers and limitations in sensitivity, simultaneous quantification of multiple BAs remains a challenge.. The aim of this study is to establish an accurate and sensitive method for the determination of multiple BAs with similar polarity.

    Article Title: Effect of a High-Fat Diet on the Small-Intestinal Environment and Mucosal Integrity in the Gut-Liver Axis
    Article Snippet: Briefly, the small-intestinal content was homogenized in 1000 μL of methanol containing cholic acid-d4 (d4-CA) (Cayman Chemical Company, MI, USA), chenodeoxycholic acid-d4 (d4-CDCA) (Cayman Chemical Company), taurocholic acid-d5 (d5-TCA) (Toronto Research Chemicals, Inc., North York, Canada), taurochenodeoxycholic acid-d4 (d4-TCDCA) (Cayman Chemical Company), glycocholic acid-d4 (d4-GCA) (Cayman Chemical Company), deoxycholic acid-d4 (d4-DCA) (Cayman Chemical Company), lithocholic acid-d4 (d4-LCA) (Cayman Chemical Company) and glycodeoxycholic acid-d4 (d4-GDCA) (Santa Cruz Biotechnology Inc., CA, USA) as the internal standards.

    High Content Screening:

    Article Title: Rhizome of Atractylodes macrocephala Alleviates Spleen-Deficiency Constipation in Rats by Modulating Gut Microbiota and Bile Acid Metabolism.
    Article Snippet: This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record.. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article.. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

    Article Title: Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids.
    Article Snippet: .. Material 7-keto-25-hydroxycholesterol (7-keto-25-OHC), 7-keto-27-hydroxycholesterol (7-keto-27-OHC), 7α,24(S)-dihydroxycholesterol (7α,24(S)-diOHC), 7α,25-dihydroxycholesterol (7α,25-diOHC), 7α,27dihydroxycholesterol (7α,27-diOHC), 5α,6β-dihydroxycholesterol (5α,6β-diOHC), 7α,12αdihydroxycholestenone (7α,12α-diOHCone), 7-ketocholesterol (7-ketochol), 4β-hydroxycholesterol (4βOHC), 7α-hydroxycholesterol (7α-OHC), 22(R)-hydroxycholesterol (22(R)-OHC), 24(S)hydroxycholesterol (24(S)-OHC), 25-hydroxycholesterol (25-OHC), 27-hydroxycholesterol (27-OHC), 7αhydroxycholestenone (7α-OHCone), 5α,6α-epoxycholesterol (5α,6α-epoxychol), 5β,6β-epoxycholesterol (5β,6β-epoxychol), 24(S),25-epoxycholesterol (24(S),25-epoxychol), [25,26,26,26,27,27,27-2H7]4βhydroxycholesterol (d7-4β-OHC) and [25,26,26,26,27,27,27- 2H7]24(R/S)-hydroxycholesterol (d7-24-OHC) were purchased from Avanti Polar Lipids (Table 2). α-muricholic acid (α-MCA), β-muricholic acid (β-MCA), ω-muricholic acid (ω-MCA), hyocholic acid (HCA), cholic acid (CA), chenodeoxycholic acid (CDCA), hyodeoxycholic acid (HDCA), murideoxycholic acid (MDCA), ursodeoxycholic acid (UDCA), deoxycholic acid (DCA), lithocholic acid (LCA), tauro-αmuricholic acid (Tα-MCA), tauro-β-muricholic acid (Tβ-MCA), tauro-ω-muricholic acid (Tω-MCA), taurocholic acid (TCA), taurochenodeoxycholic acid (TCDCA), taurohyodeoxycholic acid (THDCA), tauroursodeoxycholic acid (TUDCA), taurodeoxycholic acid (TDCA), taurolithocholic acid (TLCA), Jo urn al Pr e-p roo f 5 glycocholic acid (GCA), glycochenodeoxycholic acid (GCDCA), glycohyodeoxycholic acid (GHDCA), glycourseodeoxycholic acid (GUDCA), glycodeoxycholic acid (GDCA), glycolithocholic acid (GLCA), [2,2,4,4-2H4]cholic acid (d4-CA), [2,2,4,4- 2H4]chenodeoxycholic acid (d4-CDCA), [2,2,4,4- 2H4]lithocholic acid (d4-LCA), [2,2,4,4- 2H4]taurocholic acid (d4-TCA), [2,2,4,4- 2H4]glycocholic acid (d4-GCA) were purchased from Cayman Chemical (Table 2). ..



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    Millipore chenodeoxycholic acid-d4 (cdca-d4
    Concentration ratios of significantly differential metabolites among the three groups the pathways of lipids. *P<0.05 and FDR <0.05 for drug-15 days compared with baseline; # P<0.05 and FDR <0.05 for drug-30 days compared with baseline. FDR, false discovery rate; <t>CDCA,</t> <t>chenodeoxycholic</t> acid; UDCA, ursodeoxycholic acid.
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    Image Search Results


    Concentration ratios of significantly differential metabolites among the three groups the pathways of lipids. *P<0.05 and FDR <0.05 for drug-15 days compared with baseline; # P<0.05 and FDR <0.05 for drug-30 days compared with baseline. FDR, false discovery rate; CDCA, chenodeoxycholic acid; UDCA, ursodeoxycholic acid.

    Journal: Annals of Translational Medicine

    Article Title: Effect of roxadustat on serum metabolome and lipidome in patients with end-stage renal disease and erythropoiesis-stimulating agent resistance

    doi: 10.21037/atm-22-4451

    Figure Lengend Snippet: Concentration ratios of significantly differential metabolites among the three groups the pathways of lipids. *P<0.05 and FDR <0.05 for drug-15 days compared with baseline; # P<0.05 and FDR <0.05 for drug-30 days compared with baseline. FDR, false discovery rate; CDCA, chenodeoxycholic acid; UDCA, ursodeoxycholic acid.

    Article Snippet: Carnitine (Car) C2:0-d3, Car C10:0-d3, Car C16:0-d3, phenylalanine-d5 (Phe-d5), tryptophan-d5 (Trp-d5), cholic acid-d4 (CA-d4), and chenodeoxycholic acid-d4 (CDCA-d4) were purchased from Sigma-Aldrich and used as the internal standards (IS) for metabolomic profiling.

    Techniques: Concentration Assay

    Bile acids changes during drug treatment. (A) Concentration ratios of significantly differential bile acids among the three groups; (B) pathways of bile acids. *P<0.05 and FDR <0.05 for drug-15 days compared with baseline; # P<0.05 and FDR <0.05 for drug-30 days compared with baseline. FDR, false discovery rate; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; GCA, glycocholic acid; GCDCA, glycochenodeoxycholic acid; GDCA, glycodeoxycholic acid; GLCA, glycolithocholic acid; GUDCA, glycoursodeoxycholic acid; LCA, lithocholic acid; TCA,taurocholic acid; TCDCA, taurochenodeoxycholicacid; TDCA, tauroursodeoxycholic acid; TLCA, taurolithocholic acid; TUDCA, tauroursodeoxycholic acid; UDCA, ursodeoxycholic acid.

    Journal: Annals of Translational Medicine

    Article Title: Effect of roxadustat on serum metabolome and lipidome in patients with end-stage renal disease and erythropoiesis-stimulating agent resistance

    doi: 10.21037/atm-22-4451

    Figure Lengend Snippet: Bile acids changes during drug treatment. (A) Concentration ratios of significantly differential bile acids among the three groups; (B) pathways of bile acids. *P<0.05 and FDR <0.05 for drug-15 days compared with baseline; # P<0.05 and FDR <0.05 for drug-30 days compared with baseline. FDR, false discovery rate; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; GCA, glycocholic acid; GCDCA, glycochenodeoxycholic acid; GDCA, glycodeoxycholic acid; GLCA, glycolithocholic acid; GUDCA, glycoursodeoxycholic acid; LCA, lithocholic acid; TCA,taurocholic acid; TCDCA, taurochenodeoxycholicacid; TDCA, tauroursodeoxycholic acid; TLCA, taurolithocholic acid; TUDCA, tauroursodeoxycholic acid; UDCA, ursodeoxycholic acid.

    Article Snippet: Carnitine (Car) C2:0-d3, Car C10:0-d3, Car C16:0-d3, phenylalanine-d5 (Phe-d5), tryptophan-d5 (Trp-d5), cholic acid-d4 (CA-d4), and chenodeoxycholic acid-d4 (CDCA-d4) were purchased from Sigma-Aldrich and used as the internal standards (IS) for metabolomic profiling.

    Techniques: Concentration Assay